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Partnerships

National or international APS clinical research studies that have been conducted based
on the collaborative efforts of APS ACTION members:
Project Name Principal Investigator(s) APS ACTION Collaborators Start Date Current Status More Information
Euro-Phospholipid Project Ricard Cervera Ronald Derksen, Munther Khamashta, Pier Luigi Meroni, Phlipp De Groot, Angela Tincani 2001 Active Eurolupus

Catastrophic APS Registry

 Ricard Cervera Doruk Erkan 1998 Active CAPS Registry
PROMISSE: Predictors of Pregnancy Outcomes in APS and SLE Jane Salmon Ware Branch,
Michael Lockshin,
Munther Khamashta		 2003 Active Clinicaltrials.gov
RITAPS: A Pilot Study of Rituximab for the Anticoagulation Resistant Manifestations of APS Doruk Erkan Michael Lockshin 2007 Active Clinicaltrials.gov
Effects of Fluvastatin on Pro-inflammatory and Pro-thrombotic Markers in APS Patients

Doruk Erkan,
Silvia Pierangeli

 Michael Lockshin 2008 Closed Clinicaltrials.gov
Stroke and aPL: Community-Based Clinicopathological Study Steven Levine

Robin Brey,
Jacob Rand

 2009 Active Nih.gov
Effects of Hydroxychloroquine on the Annexin A5 Resistance Assay in aPL-Positive Patients with and without SLE Doruk Erkan

Michael Lockshin, Jacob Rand

 2011 Active Alana Levine,
MD at hcqstudy@hss.edu
Vascular, Cognitive, and Motor Decline: Impact of aPL Zoe Arvanitakis

Robin Brey,
Steven Levine

 2011 Pending Pending